7:45 AM - 8:45 AM

Registration & Breakfast

8:45 AM - 9:00 AM

Chairman’s Opening Remarks

Smart Pharma: Key Trends That Will Enable The Reshaping of Drug Discovery and Development

This opening session will set the stage for the discussions that will take place over the course of the Summit and identify the key trends that are taking hold in biopharma and reshaping drug discovery and clinical development. Themes will include:

  • Rapid adoption of digitization in drug discovery and clinical trials.
  • Precision medicine’s impact on drug development.
  • The evolution and implications of new models in clinical trial recruitment.
  • The changing partnership ecosystem – biopharma, technology platforms, investors, regulatory and patients.
Harry Glorikian | Speaking at AI Applications Summit | Biopharma

Harry Glorikian

General Partner New Ventures Funds
9:00 AM - 9:40 AM

Executive Viewpoints: Will AI Be Innovation or Renovation for Biopharma?

Moderator

Milind Kamkolkar | Speaking at AI Applications Summit | Biopharma

Dr. Milind Kamkolkar

Chief Data Officer Cellarity - a Flagship Pioneering Company

Speakers

Dimitris Agrafiotis, Ph.D., FRSC

Chief Information Officer Novartis Institutes for Biomedical Research

Disrupting the Status Quo With Visionary Models For Collaboration

9:40 AM - 10:05 AM

Internal Collaboration: Moving Toward the Value of End-to-End Machine Learning for Pipeline Optimization

Alex Zhavoronkov, Ph.D., CEO, Insilico Medicine, Inc

Alex Zhavoronkov, Ph.D.

CEO Insilico Medicine, Inc
10:05 AM - 10:30 AM

The Handbook on how to Find the Right External Partners

Drug Discovery

10:30 AM - 10:55 AM

Early Stage R&D Use Cases

10:55 AM - 11:25 AM

Networking, Refreshments & Expert One-to-One Meetings

11:25 AM - 11:50 AM

Late Stage R&D Use Cases

11:50 AM - 12:15 PM

Employing AI to find the Translational Piece for Making Drugs Effective, Validated and Useful in Humans

Case Study: Achieving Higher Success Rates of Translation from Biology to Pre-Clinical, and from Pre-Clinical to Clinical Programs by
Brandon Allgood, CTO and Co-Founder, Numerate

Gina Deshpande | Speaker | AI Applications Summit

Gini Deshpande, PhD

CEO & Founder NuMedii
Brandon Allgood

Brandon Allgood

CTO and Co-Founder Numerate
12:15 PM - 1:15 PM

Networking Lunch & Expert One-to-One Meetings

AI for Clinical Development

1:15 PM - 1:40 PM

Using Deep Learning to Improve Drug Development Success Outcomes

This session will look at how AI technology such as Deep Learning is being applied to the challenge of drug failure, both in discovery and in clinical trials. One of the primary drivers of R&D expense is the high number of failures that occur during the development of a therapeutic. Many pharmaceutical companies are now looking at AI solutions to better predict which assets will succeed in trials, and to design compounds have been optimized for success. Some specific examples:

  • Using clinical trial outcomes to improve estimates of success.
  • Currently approximately 50% of trials fail due to ADME/Tox issues – examples of how Pfizer is using DL to help change this.
  • How is medicinal chemistry and design changing with AI?
  • Using AI earlier in the discovery cycle to select targets and indications for investment.
Michael G Frank | Speaker | AI Applications Summit

Michael G. Frank

Director, World Wide R&D Strategy Pfizer
1:40 PM - 2:05 PM

Realizing the Potential of Virtual and Hybrid Clinical Trials

The need to increase the speed of patient recruitment, improve retention, and enhance data quality – all while lowering costs, has led to the current interest in virtual and hybrid clinical trials. The question is, how do you know when a virtual or hybrid study makes sense? This session will focus on the critical differences between traditional and virtual or hybrid trials that need to be considered.

  • What therapeutic areas are most effective using virtual and hybrid trials?
  • The importance of protocol design and a distribution and tracking plan for medication.
  • What steps need to be taken to ensure the safety of patients?
  • If the home is the new trial site, how is that different? What do you need to do differently from the start of the process through the end of the trial?
Nitin Naik | Speaker | AI Applications Summit

Nitin Naik

Vice President-Global Life Sciences, Transformational Health Frost & Sullivan
Dr. Michelle Longmire, CEO & Co-Founder, Medable

Dr. Michelle Longmire

CEO & Co-Founder Medable
2:05 PM - 2:35 PM

Getting to the Proof of Innovation: Case Studies From AI Use in Clinical Trials

2:35 PM - 3:05 PM

Afternoon Refreshments & Expert One-to-One Meetings

3:05 PM - 3:55 PM

Deep Dive Concurrent Sessions

Clinical Development

Mohammed Ali | Speaker | AI Applications Summit

Mohammed Ali

Global Head Digital Trials- Global Clinical Operations Boehringer Ingelheim Pharmaceuticals, Inc.

Data Democratization & Interoperability

Ed Bowen

Vice President, AI & Machine Learning, Medicinal Science and Technology (MST) GSK

Discovery

Brian S. Martin, Head of AI R&D Information Research, AbbVie

Brian S. Martin

Head of AI R&D Information Research AbbVie
4:00 PM - 4:25 PM

An AI Powered Project: Human Genetics & Drug Discovery

This session will discuss the UK Biobank project and its potential impact on the industry when the big data derived from the human genome is married with breakthroughs from artificial intelligence.

Moderator

Gunaretnam Rajagopal | Speaker | AI Applications Summit

Dr. Gunaretnam (Guna) Rajagopal

VP Global Head – Computational Sciences, Discovery Sciences Janssen Research & Development, A Johnson & Johnson Company
4:25 PM - 5:00 PM

Innovation Spotlight Changemaker Presentations

The Innovation Spotlight Presentation program features six changemaker speakers along with moderator Travis McCready, President & CEO of Massachusetts Life Sciences Center. Each speaker presents a concise and fast-paced 5-minute presentation that will introduce you to an innovative way of solving a problem, a new technology or tool, or a transformative approach to solving common issues facing biopharma companies today. Immediately following the spotlight presentations, attendees can meet with these innovative companies in a relaxed atmosphere during the evening reception.

Moderator

Travis McCready | Speaker | AI Applications Summit

Travis A. McCready

President & CEO Massachusetts Life Sciences Center

Changemaker Presenters

Richie Bavasso

CEO & Co-Founder nQ Medical Inc.
Matthew A. Michela, President and CEO, Life Image

Matthew A. Michela

President and CEO Life Image
David Wild, Ph.D | Speaker | AI Applications Summit

David Wild, Ph.D.

Founder & President Data2Discovery Inc
5:00 PM - 6:00 PM

Evening Reception

8:00 AM - 9:00 AM

Breakfast & Expert One-to-One Meetings

Real-World Evidence

9:00 AM - 9:25 AM

Overcoming Barriers to RWE Adoption and Realizing Value

Moderator

Janak Joshi, Senior Vice President, Chief of Technology and Head of Strategy, Life Image

Janak Joshi

Senior Vice President, Chief of Technology and Head of Strategy Life Image

Speaker

Charles Makin | Speaker | AI Applications Summit

Charles Makin

Global Head, Real World Evidence Strategy Biogen
Jennifer L. Wong, Senior Director, Real World Evidence Strategy & Alliances, AstraZeneca

Jennifer L. Wong

Senior Director, Real World Evidence Strategy & Alliances AstraZeneca
9:25 AM - 9:50 AM

Innovate Practically: Finding the Intersections Between AI and RWE to Better Treat Patients

This session will cover how biopharma companies are using real world data combined with AI to enhance business value and impact. While still in the nascent stages, the practice of real-world data analytics is moving beyond primarily post-approval applications and is being institutionalized across organizations. Themes to be discussed include:

  • Overcoming cultural resistance to using real world data.
  • Adopting and effectively utilizing real-world evidence to develop the innovative medicines of the future.
  • Collaborating with strategic partners to identify specific use cases that advance your efforts and deliver beneficial therapies faster to patients.
Chris Boone Ph.D | Speaker | AI Applications Summit

Christopher Boone, Ph.D, FACHE

Vice President, Head of Real World Data and Analytics Center of Excellence Pfizer
Mimi Huizinga, MD MPH FACP, VP, Strategic Data and Digital, US Oncology, Novartis Pharmaceuticals Corporation

Mimi Huizinga, MD MPH FACP

VP, Strategic Data and Digital, US Oncology Novartis Pharmaceuticals Corporation
9:50 AM - 10:15 AM

FDA's Real-World Evidence Program

This session will cover the main elements of the framework for FDA’s real-world evidence program and will describe ongoing demonstration projects and collaborations. The emerging and evolving role of technological innovations in facilitating the use of real-world data will be discussed and highlighted. Examples of activities focused on the utilization of AI to support the development of therapeutics will be provided.

M. Khair ElZarrad Ph.D., MPH, Deputy Director, Office of Medical Policy

M. Khair ElZarrad Ph.D., MPH

Deputy Director, Office of Medical Policy Center for Drug Evaluation and Research, U.S. Food and Drug Administration (FDA)

Data Management

10:15 AM - 10:40 AM

Data Diversity and Access: Impacting Patients in Meaningful Ways and Avoiding Data Biases

Gabriela Lavezzari

Senior Director, US R&D Policy & Scientific Affairs, R&D Strategy, Portfolio & Operations GSK
10:40 AM - 11:10 AM

Morning Refreshments & Expert One-to-One Meetings

11:10 AM - 11:35 AM

Data Organization and Communication: Unlocking the Value of Insights

This session features two case study presentations that will address the importance of data organization across an organization to unlock the value of the data being collected.

  • Why one-size-fits-all systems don’t work (at least right now).
  • Janssen’s “ecosystem of platforms” approach to taking existing systems for different purposes and integrating them for better data access.
  • Methods for capturing data sets to do analysis across the company instead of in silos.
  • A view into current Janssen projects.

Bhaskar Dutta

Principal Scientist, Advanced Analytics Center AstraZeneca
Joseph Lehar | Speaker | AI Applications Summit

Joseph Lehar

VP of Data Science, Oncology The Janssen Pharmaceutical Companies of Johnson & Johnson
11:35 AM - 12:00 PM

Confessions of a Data Scientist in Pharma: Working in an Analog Industry in a Digital World

In this session Aman will talk about his experience managing data science across all of Vertex and lead a discussion about the triumphs and tribulations of being a data scientist in pharma. Themes to be covered include:

  • Steps to becoming a data-driven company across all functional areas.
  • How do you institutionalize operational effectiveness?
  • What are the key elements to building a data science culture with alignment across the organization?
  • How can you compete for talent?
  • How can you manage the hype around savings and success?
  • Managing through the Tower of Babel of data.

Aman Bhandari

VP, Data Science, Data Strategy and Solutions Vertex Pharmaceuticals
12:00 PM - 12:40 PM

Open Discussion: New Collaborative Models to Impact Patients in More Meaningful Ways

Several industry pioneers will lead an audience-wide discussion on the collaborative models in use that are impacting patients now. This is your unique opportunity to gain an understanding of how industry peers are innovating via collaborative models with each other, technology partners and academia. This is also a great opportunity to expand your network and possibly find your next partner.

Niven Narain | Speaker | AI Applications Summit

Niven R. Narain Ph.D.

Co-Founder, President & CEO BERG
Jennifer L. Wong, Senior Director, Real World Evidence Strategy & Alliances, AstraZeneca

Jennifer L. Wong

Senior Director, Real World Evidence Strategy & Alliances AstraZeneca
12:40 PM - 12:45 PM

Chair's Closing Remarks