Alex Zhavoronkov, Ph.D., Insilico Medicine, Inc

Alex Zhavoronkov, Ph.D. Dr. Zhavoronkov is the founder and CEO of Insilico Medicine, a Baltimore-based leader in the next-generation AI for drug discovery, biomarker development, and aging research. Prior to Insilico, he worked in senior roles at ATI Technologies, NeuroG Neuroinformatics, the Biogerontology Research Foundation and co-founded YLabs.AI. Since 2012 he published over 100 peer-reviewed research papers and two books. He organizes the annual Aging Forum and Artificial Intelligence for Healthcare Forum at EMBO/Basel Life in Basel. Dr. Zhavoronkov is an adjunct professor at the Buck Institute for Research on Aging.


10:50 AM - 11:15 AM

The Power of GANs and RL in pharma R&D: from Experimentally-Validated End-to-End Drug Discovery Pipelines to Generation of Synthetic Patients

GANs and GAN-RL systems are powerful tool for a plethora of drug discovery and biomarker development applications. The application of GANs for small molecule generation was pioneered by the scientists at Insilico Medicine with the first peer-reviewed paper titled "The cornucopia of meaningful leads" followed by series of the theoretical and experimental research papers. This session will cover usage of GAN’s by biopharmaceutical companies for:
  • Synthetic data generation
  • Extracting useful targets
  • Building causal graphs
  • Simulating drug response and CRISPR data
  • Generation of molecules with specific properties
  • Generating molecules to a specific objective

11:15 AM - 11:45 AM

How do you Build/Modify your Organization around Data Strategy – Know what questions to ASK!


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